A bioactive flavonoid from Pavetta crassipes K. Schum

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A bioactive flavonoid from Pavetta crassipes K. Schum

BACKGROUND In our continued search for bioactive compounds from plants, conscious effort is being made to rapidly analyze ethnobotanical plants used for treating various ailments by traditional healers before this information is irrevocably lost as societies advance and rural communities become urbanized. RESULTS A compound isolated from the aqueous extract of Pavetta crassipes leaves showed ...

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Hypotensive activity of the ethanol extract of Pavetta crassipes leaves.

Pavetta crassipes leaf is routinely used locally in Nigeria for the management of respiratory disorders and hypertension. The hypotensive and other cardiovascular effects of Pavetta crassipes were investigated in cats and rats. The effects of the extract on rat and cat blood pressures, isolated rat atria, rat portal vein, isolated rat aorta and rat vas deferens were studied. Specific receptor a...

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Toxicological assessment of abeere seed ( Huntaria umbellata K . Schum )

Thirty age-matched healthy adult male New Zealand white rabbits (2.0 ± 0.5kg BW) were randomly divided into six groups (four treatment and two control groups). The treatment groups were given intraperitoneal injection of either 0.5ml or 1.0ml liquid extract of abeere seed or the alcoholic extract (w/v) and examined for 14 days. The effect of the seed extracts on the haematological parameters, s...

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A New Antifungal Phenolic Glycoside Derivative, Iridoids and Lignans from Alibertia sessilis (Vell.) K. Schum. (Rubiaceae)

Um novo derivado fenólico glucosilado antifúngico, 3,4,5-trimetoxifenil-1-O-β-D-(5-Osiringoila)-apiofuranosil-(1→6)-β-D-glicopiranosideo (1), juntamente com quatro iridóides conhecidos, ácido geniposídico (2), geniposídeo (3), 6α-hidroxigeniposideo (4) e 6βhidroxigeniposideo (5); duas lignanas, (+)-lioniresinol-3α-O-β-D-glicopiranosideo (6), (-)lioniresinol-3α-O-β-D-glicopiranosideo (7); e dois...

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Antimicrobial and cytotoxic activities of extracts from Sterculia quinqueloba (Garcke) K. Schum and Canthium crassum Hiern

Sterculia quinqueloba (Garcke) K. Schum and Canthium crassum Hiern extracts were evaluated for antimicrobial activity using 96-well-microtitre serial micro-dilution method against Vibrio cholera, Klebsiella oxytoca, Klebsiella pneumonia, Streptococcus pyogenes, Staphylococcus aureus and Candida albicans. All extracts exhibited antimicrobial activity with minimum inhibition concentration range o...

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ژورنال

عنوان ژورنال: Organic and Medicinal Chemistry Letters

سال: 2011

ISSN: 2191-2858

DOI: 10.1186/2191-2858-1-14